How Many Missions In Destroy All Humans Complete Mission Count Explained

The iconic alien invasion classic Destroy All Humans features a structured campaign filled with quirky objectives, satire, and sci-fi destruction. Players stepping into the boots of Crypto-137 often want to know exactly how much content lies ahead before achieving total global dominance. Understanding the complete mission count helps players track their progress across each sandbox location.
Total Story Missions in the Campaign
The original game and its modern remake feature 22 main story missions in total. In the 2020 remake version, developers restored a restored lost mission titled The Wrong Stuff in Area 42, bringing the complete campaign count to 23 missions. These core assignments guide Crypto through distinct invasion sites ranging from quiet rural farmland to major military bases.
Breakdown of Invasion Sites
Story missions are divided across six primary open-world locations in the game. You begin your journey at Turnipseed Farm before progressing through Rockwell, Santa Modesta, and Area 42. The final narrative arc takes place in Union Town and Capitol City, where Crypto confronts high-level government threats.
Optional Challenges and Side Activities
Beyond the core campaign, players can tackle numerous optional side challenges scattered across each map. These activities are split into four distinct types: Race, Rampage, Abduction, and Armageddon challenges. Completing these optional objectives rewards additional DNA points required to upgrade Crypto's weapons, abilities, and saucer systems.
Replaying Missions for Full Completion
Players aiming for 100% completion can access previously completed assignments through the mothership menu. Utilizing the Holopoxdeck allows you to revisit any mission to finish missed optional objectives or retry challenges with fully upgraded gear. This structure ensures plenty of replayability long after the final story campaign is finished.